\n N\u1ed8I DUNG\n <\/div>\n

1. T\u1ea7m quan tr\u1ecdng c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down <\/a><\/li>\n
2. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down<\/a><\/li>\n
3. Ai n\u00ean th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down?<\/a><\/li>\n<\/ul>\n<\/div>\n
H\u1ed9i ch\u1ee9ng Down<\/a>, hay c\u00f2n g\u1ecdi l\u00e0 Tam nhi\u1ec5m s\u1eafc th\u1ec3 21 (Trisomy 21), l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n di truy\u1ec1n trong \u0111\u00f3 s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a m\u1ed9t nhi\u1ec5m s\u1eafc th\u1ec3 ph\u1ee5 g\u00e2y ra s\u1ef1 ch\u1eadm ph\u00e1t tri\u1ec3n<\/a> c\u1ea3 v\u1ec1 tinh th\u1ea7n v\u00e0 th\u1ec3 ch\u1ea5t \u1edf tr\u1ebb.<\/p>\n
\u0110\u00e2y l\u00e0 m\u1ed9t trong nh\u1eefng d\u1ecb t\u1eadt b\u1ea9m sinh di truy\u1ec1n ph\u1ed5 bi\u1ebfn nh\u1ea5t, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn kho\u1ea3ng 1\/830 ca sinh s\u1ed1ng. Nh\u1edd nh\u1eefng ti\u1ebfn b\u1ed9 trong khoa h\u1ecdc y t\u1ebf, H\u1ed9i ch\u1ee9ng Down hi\u1ec7n nay c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n t\u1eeb nh\u1eefng giai \u0111o\u1ea1n \u0111\u1ea7u c\u1ee7a thai k\u1ef3.<\/p>\n
1. T\u1ea7m quan tr\u1ecdng c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down <\/strong><\/h2>\n\n
\n $\"C\u00e1c$ \n <\/div>
\n
C\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh r\u1ea5t quan tr\u1ecdng v\u00ec ch\u00fang gi\u00fap ph\u00e1t hi\u1ec7n s\u1edbm nguy c\u01a1 thai nhi m\u1eafc H\u1ed9i ch\u1ee9ng Down v\u00e0 nhi\u1ec1u d\u1ecb t\u1eadt b\u1ea9m sinh kh\u00e1c.<\/p>\n<\/figcaption><\/figure>\n
X\u00e9t nghi\u1ec7m di truy\u1ec1n<\/a> l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 y h\u1ecdc v\u00f4 c\u00f9ng m\u1ea1nh m\u1ebd, kh\u00f4ng ch\u1ec9 gi\u00fap d\u1ef1 \u0111o\u00e1n s\u1ee9c kh\u1ecfe t\u01b0\u01a1ng lai c\u1ee7a m\u1ed9t \u0111\u1ee9a tr\u1ebb m\u00e0 c\u00f2n \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c t\u00ecm hi\u1ec3u nguy\u00ean nh\u00e2n g\u00e2y v\u00f4 sinh, s\u1ea3y thai v\u00e0 t\u1ef7 l\u1ec7 chung c\u1ee7a c\u00e1c d\u1ecb t\u1eadt b\u1ea9m sinh. S\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh gi\u00fap gi\u1ea3m b\u1edbt g\u00e1nh n\u1eb7ng c\u1ee7a c\u00e1c b\u1ec7nh di truy\u1ec1n v\u00e0 khuy\u1ebft t\u1eadt b\u1ea9m sinh<\/a> g\u00e2y suy gi\u1ea3m ch\u1ee9c n\u0103ng \u0111\u00e1ng k\u1ec3 sau khi sinh. Ph\u1ee5 n\u1eef \u0111\u00e3 tr\u1ea3i qua nhi\u1ec1u l\u1ea7n s\u1ea3y thai c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng s\u00e0ng l\u1ecdc di truy\u1ec1n \u0111\u1ec3 theo d\u00f5i s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a thai nhi m\u1ed9t c\u00e1ch th\u01b0\u1eddng xuy\u00ean.<\/p>\n
2. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p <\/strong>x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down <\/strong>
<\/h2>\n
C\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc ho\u1eb7c ngay khi th\u1ee5 thai<\/a>, \u0111\u00f3ng vai tr\u00f2 nh\u01b0 m\u1ed9t t\u1ea5m b\u1ea3n \u0111\u1ed3 gene, gi\u00fap c\u1eb7p \u0111\u00f4i n\u1eafm r\u00f5 nguy c\u01a1 sinh s\u1ea3n c\u1ee7a m\u00ecnh.<\/p>\n
2.1. S\u00e0ng l\u1ecdc tr\u01b0\u1edbc h\u00f4n nh\u00e2n ho\u1eb7c tr\u01b0\u1edbc khi mang thai <\/em><\/strong><\/h3>\n
S\u00e0ng l\u1ecdc tr\u01b0\u1edbc h\u00f4n nh\u00e2n ho\u1eb7c tr\u01b0\u1edbc khi mang thai gi\u00fap c\u1eb7p \u0111\u00f4i bi\u1ebft \u0111\u01b0\u1ee3c li\u1ec7u con c\u00e1i c\u1ee7a h\u1ecd c\u00f3 nguy c\u01a1 m\u1eafc b\u1ea5t k\u1ef3 b\u1ec7nh di truy\u1ec1n n\u00e0o hay kh\u00f4ng. Ph\u01b0\u01a1ng ph\u00e1p n\u00e0y \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng n\u1ebfu b\u1ec7nh l\u00fd \u0111\u00f3 c\u00f3 ti\u1ec1n s\u1eed gia \u0111\u00ecnh. Trong m\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p, s\u00e0ng l\u1ecdc c\u00f2n l\u00e0 m\u1ed9t bi\u1ec7n ph\u00e1p ph\u00f2ng ng\u1eeba h\u1eefu hi\u1ec7u.<\/p>\n
S\u00e0ng l\u1ecdc ng\u01b0\u1eddi mang gene b\u1ec7nh: <\/b><\/em><\/p>\n
\n
\n
\n
$\"H\u1ed9i$ <\/a>
\n
H\u1ed9i ch\u1ee9ng Down \u0111i\u1ec1u tr\u1ecb nh\u01b0 th\u1ebf n\u00e0o?<\/a>\u0110\u1eccC NGAY<\/span><\/p>\n
\n <\/i>\n <\/div>\n
<\/a><\/h4>\n<\/li>\n<\/ul><\/div>\n<\/div>\n
\u0110\u00e2y l\u00e0 ph\u01b0\u01a1ng ph\u00e1p n\u1ec1n t\u1ea3ng, th\u1ef1c hi\u1ec7n tr\u00ean nh\u1eefng c\u00e1 nh\u00e2n ho\u00e0n to\u00e0n kh\u1ecfe m\u1ea1nh (kh\u00f4ng bi\u1ec3u hi\u1ec7n b\u1ec7nh) nh\u01b0ng c\u00f3 th\u1ec3 mang trong m\u00ecnh m\u1ed9t gene bi\u1ebfn th\u1ec3 li\u00ean quan \u0111\u1ebfn b\u1ec7nh l\u00fd.<\/p>\n
Th\u00f4ng tin s\u00e0ng l\u1ecdc ng\u01b0\u1eddi mang gene n\u00ean \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n cho m\u1ecdi ph\u1ee5 n\u1eef mang thai, nh\u01b0ng l\u00fd t\u01b0\u1edfng nh\u1ea5t l\u00e0 th\u1ef1c hi\u1ec7n tr\u01b0\u1edbc khi mang thai. \u0110i\u1ec1u n\u00e0y cho ph\u00e9p c\u00e1c c\u1eb7p \u0111\u00f4i hi\u1ec3u r\u00f5 nguy c\u01a1 c\u1ee7a m\u00ecnh v\u00e0 c\u00e2n nh\u1eafc ph\u1ea1m vi l\u1ef1a ch\u1ecdn sinh s\u1ea3n \u0111\u1ea7y \u0111\u1ee7 nh\u1ea5t.<\/p>\n
Ch\u1eb3ng h\u1ea1n nh\u01b0, n\u1ebfu ng\u01b0\u1eddi v\u1ee3 mang gene b\u1ec7nh Thalassemia, vi\u1ec7c x\u00e9t nghi\u1ec7m \u0111\u1ed1i t\u00e1c s\u1ebd gi\u00fap c\u1eb7p \u0111\u00f4i nh\u1eadn \u0111\u01b0\u1ee3c t\u01b0 v\u1ea5n di truy\u1ec1n chuy\u00ean s\u00e2u, hi\u1ec3u r\u00f5 nguy c\u01a1 sinh con m\u1eafc b\u1ec7nh v\u00e0 ch\u1ee7 \u0111\u1ed9ng \u0111\u01b0a ra quy\u1ebft \u0111\u1ecbnh.<\/p>\n
S\u00e0ng l\u1ecdc \u0111\u1ed9t bi\u1ebfn gene<\/b><\/em><\/p>\n
Ph\u01b0\u01a1ng ph\u00e1p n\u00e0y \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n khi m\u1ed9t t\u00ecnh tr\u1ea1ng di truy\u1ec1n \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n ho\u1eb7c c\u00f3 ti\u1ec1n s\u1eed gia \u0111\u00ecnh. N\u00f3 c\u00f3 th\u1ec3 ph\u00e1t hi\u1ec7n c\u00e1c b\u1ec7nh do \u0111\u1ed9t bi\u1ebfn ho\u1eb7c nucleotit trong gene g\u00e2y ra.<\/p>\n
Gi\u1ea3i tr\u00ecnh t\u1ef1 to\u00e0n b\u1ed9 Exome<\/b><\/em><\/p>\n
Kho\u1ea3ng 85% c\u00e1c bi\u1ebfn th\u1ec3 g\u00e2y b\u1ec7nh \u0111\u00e3 bi\u1ebft x\u1ea3y ra trong 1% b\u1ed9 gene ch\u1ee9a c\u00e1c exon v\u00e0 v\u00f9ng n\u1ed1i. Do \u0111\u00f3, vi\u1ec7c kh\u1ea3o s\u00e1t ri\u00eang ph\u1ea7n n\u00e0y c\u1ee7a b\u1ed9 gene l\u00e0 m\u1ed9t c\u00f4ng c\u1ee5 ch\u1ea9n \u0111o\u00e1n l\u00e2m s\u00e0ng m\u1ea1nh m\u1ebd v\u00e0 hi\u1ec7u qu\u1ea3. B\u1eb1ng c\u00e1ch kh\u1ea3o s\u00e1t h\u1ea7u nh\u01b0 t\u1ea5t c\u1ea3 c\u00e1c v\u00f9ng m\u00e3 h\u00f3a protein trong b\u1ed9 gene b\u1eb1ng x\u00e9t nghi\u1ec7m \u0111\u01a1n l\u1ebb n\u00e0y, ph\u01b0\u01a1ng ph\u00e1p n\u00e0y thay th\u1ebf nhu c\u1ea7u ti\u1ec1m n\u0103ng v\u1ec1 nhi\u1ec1u x\u00e9t nghi\u1ec7m gi\u1ea3i tr\u00ecnh t\u1ef1 gene \u0111\u01a1n l\u1ebb t\u1ed1n k\u00e9m, \u0111\u1ed3ng th\u1eddi c\u1ea3i thi\u1ec7n \u0111\u00e1ng k\u1ec3 kh\u1ea3 n\u0103ng x\u00e1c \u0111\u1ecbnh bi\u1ebfn th\u1ec3 r\u1ee7i ro cao \u0111\u1ec3 h\u01b0\u1edbng d\u1eabn qu\u1ea3n l\u00fd l\u00e2m s\u00e0ng ph\u00f9 h\u1ee3p. Trung b\u00ecnh, 20.000 bi\u1ebfn th\u1ec3 DNA trong exon \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n \u1edf m\u1ed7i b\u1ec7nh nh\u00e2n.<\/p>\n
2.2. S\u00e0ng l\u1ecdc trong thai k\u1ef3 <\/em><\/strong><\/h2>\n
Sau khi th\u1ee5 thai, c\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y gi\u00fap theo d\u00f5i s\u00e1t sao t\u00ecnh tr\u1ea1ng ph\u00e1t tri\u1ec3n v\u00e0 s\u1ee9c kh\u1ecfe c\u1ee7a thai nhi trong su\u1ed1t thai k\u1ef3.<\/p>\n
X\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh kh\u00f4ng x\u00e2m l\u1ea5n (NIPT<\/a>)<\/b><\/em><\/p>\n
NIPT l\u00e0 x\u00e9t nghi\u1ec7m m\u00e1u \u0111\u01a1n gi\u1ea3n c\u1ee7a m\u1eb9, t\u00ecm ki\u1ebfm c\u00e1c b\u1ea5t th\u01b0\u1eddng trong th\u00f4ng tin di truy\u1ec1n (DNA) c\u1ee7a thai nhi l\u01b0u th\u00f4ng trong m\u00e1u m\u1eb9.<\/p>\n
\u0110\u1ed9 nh\u1ea1y cao: X\u00e9t nghi\u1ec7m c\u1ef1c k\u1ef3 nh\u1ea1y c\u1ea3m v\u1edbi c\u00e1c t\u00ecnh tr\u1ea1ng l\u1ec7ch b\u1ed9i nhi\u1ec5m s\u1eafc th\u1ec3 ph\u1ed5 bi\u1ebfn nh\u01b0 Tam nhi\u1ec5m s\u1eafc th\u1ec3 13, 18 v\u00e0 21 (H\u1ed9i ch\u1ee9ng Down). C\u00f4ng ngh\u1ec7 hi\u1ec7n \u0111\u1ea1i n\u00e0y gi\u00fap cha m\u1eb9 an t\u00e2m h\u01a1n v\u1ec1 vi\u1ec7c em b\u00e9 s\u1ebd \u0111\u01b0\u1ee3c sinh ra kh\u00f4ng m\u1eafc c\u00e1c v\u1ea5n \u0111\u1ec1 di truy\u1ec1n nghi\u00eam tr\u1ecdng.<\/p>\n
Ch\u1ecdc \u1ed1i <\/b><\/i><\/p>\n
\u0110\u00e2y l\u00e0 k\u1ef9 thu\u1eadt x\u00e2m l\u1ea5n \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh khi k\u1ebft qu\u1ea3 s\u00e0ng l\u1ecdc ban \u0111\u1ea7u c\u00f3 nguy c\u01a1 cao, c\u1ea7n x\u00e1c nh\u1eadn ch\u1ea9n \u0111o\u00e1n ch\u00ednh x\u00e1c.<\/p>\n
B\u00e1c s\u0129 s\u1ebd l\u1ea5y ra m\u1ed9t l\u01b0\u1ee3ng nh\u1ecf n\u01b0\u1edbc \u1ed1i (ch\u1ea5t l\u1ecfng bao quanh thai nhi) kh\u1ecfi t\u1eed cung \u0111\u1ec3 ph\u00e2n t\u00edch. N\u01b0\u1edbc \u1ed1i ch\u1ee9a t\u1ebf b\u00e0o thai nhi v\u00e0 c\u00e1c lo\u1ea1i protein.<\/p>\n
Ph\u01b0\u01a1ng ph\u00e1p ph\u00e2n t\u00edch vi m\u1ea3ng nhi\u1ec5m s\u1eafc th\u1ec3 (CMA) \u0111ang \u0111\u00f3ng vai tr\u00f2 ng\u00e0y c\u00e0ng quan tr\u1ecdng trong x\u00e9t nghi\u1ec7m tr\u01b0\u1edbc sinh. CMA c\u00f3 \u0111\u1ed9 nh\u1ea1y cao, gi\u00fap ph\u00e1t hi\u1ec7n c\u00e1c vi x\u00f3a ho\u1eb7c vi l\u1eb7p c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng m\u00e0 k\u00ednh hi\u1ec3n vi th\u00f4ng th\u01b0\u1eddng kh\u00f4ng th\u1ec3 th\u1ea5y, cung c\u1ea5p ch\u1ea9n \u0111o\u00e1n chi ti\u1ebft v\u00e0 ch\u00ednh x\u00e1c nh\u1ea5t v\u1ec1 c\u1ea5u tr\u00fac nhi\u1ec5m s\u1eafc th\u1ec3 c\u1ee7a thai nhi.<\/p>\n
3. Ai n\u00ean th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down?<\/strong><\/h2>\n
Kh\u1ea3 n\u0103ng sinh con m\u1eafc H\u1ed9i ch\u1ee9ng Down th\u01b0\u1eddng t\u1ef7 l\u1ec7 thu\u1eadn v\u1edbi tu\u1ed5i c\u1ee7a ng\u01b0\u1eddi m\u1eb9:<\/p>\n
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D\u01b0\u1edbi 25 tu\u1ed5i: Kh\u1ea3 n\u0103ng m\u1eafc H\u1ed9i ch\u1ee9ng Down kho\u1ea3ng 1\/1.400.<\/li>\n
35 tu\u1ed5i: Kh\u1ea3 n\u0103ng kho\u1ea3ng 1\/350.<\/li>\n
40 tu\u1ed5i: Kh\u1ea3 n\u0103ng kho\u1ea3ng 1\/100.<\/li>\n<\/ul>\n
X\u00e9t nghi\u1ec7m di truy\u1ec1n \u0111\u01b0\u1ee3c khuy\u1ebfn ngh\u1ecb cho nh\u1eefng ng\u01b0\u1eddi c\u00f3 nguy c\u01a1 cao sinh con m\u1eafc b\u1ec7nh di truy\u1ec1n, bao g\u1ed3m:<\/p>\n
– Ti\u1ec1n s\u1eed gia \u0111\u00ecnh: C\u00e1c gia \u0111\u00ecnh c\u00f3 b\u1ec7nh di truy\u1ec1n \u1edf ng\u01b0\u1eddi th\u00e2n g\u1ea7n, ho\u1eb7c cha m\u1eb9 \u0111\u00e3 c\u00f3 con m\u1eafc b\u1ec7nh di truy\u1ec1n.<\/p>\n
– C\u00e1c c\u1eb7p \u0111\u00f4i \u0111ang l\u00ean k\u1ebf ho\u1ea1ch c\u00f3 con: N\u1ebfu m\u1ed9t trong hai ng\u01b0\u1eddi ho\u1eb7c ng\u01b0\u1eddi th\u00e2n g\u1ea7n m\u1eafc b\u1ec7nh di truy\u1ec1n.<\/p>\n
– Ph\u1ee5 n\u1eef mang thai tr\u00ean 30 tu\u1ed5i.<\/p>\n
– Ph\u1ee5 n\u1eef tr\u00ean 34 tu\u1ed5i ho\u1eb7c \u0111\u00e3 t\u1eebng c\u00f3 hai l\u1ea7n s\u1ea3y thai tr\u1edf l\u00ean.<\/p>\n
– Ph\u1ee5 n\u1eef \u0111\u00e3 sinh con ch\u1ebft l\u01b0u v\u1edbi c\u00e1c d\u1ea5u hi\u1ec7u th\u1ec3 ch\u1ea5t c\u1ee7a r\u1ed1i lo\u1ea1n di truy\u1ec1n.<\/p>\n
– C\u1eb7p \u0111\u00f4i l\u00e0 h\u1ecd h\u00e0ng ru\u1ed9t th\u1ecbt (k\u1ebft h\u00f4n c\u1eadn huy\u1ebft).<\/p>\n
– T\u1ea5t c\u1ea3 ph\u1ee5 n\u1eef mang thai (b\u1ea5t k\u1ec3 nguy c\u01a1) trong \u0111\u1ed9 tu\u1ed5i t\u1eeb 22 \u0111\u1ebfn 50 \u0111\u1ed1i v\u1edbi c\u00e1c tr\u01b0\u1eddng h\u1ee3p c\u00f3 nguy c\u01a1 cao b\u1ea5t th\u01b0\u1eddng nhi\u1ec5m s\u1eafc th\u1ec3 \u1edf thai nhi.<\/p>\n
Vi\u1ec7c t\u00ecm \u0111\u1ebfn c\u00e1c ph\u00f2ng kh\u00e1m sinh s\u1ea3n c\u00f3 ph\u00f2ng th\u00ed nghi\u1ec7m n\u1ed9i b\u1ed9 gi\u00fap gi\u1ea3m thi\u1ec3u nguy c\u01a1 x\u1eed l\u00fd m\u1eabu sai s\u00f3t, \u0111\u1ed3ng th\u1eddi t\u0103ng c\u01b0\u1eddng t\u00ednh hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 ch\u00ednh x\u00e1c nh\u1edd \u00e1p d\u1ee5ng c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn. C\u00e1c ph\u00f2ng th\u00ed nghi\u1ec7m cung c\u1ea5p c\u00e1c x\u00e9t nghi\u1ec7m n\u00e0y c\u1ea7n \u0111\u1ea3m b\u1ea3o th\u1eddi gian tr\u1ea3 l\u1eddi nhanh ch\u00f3ng v\u1edbi chi ph\u00ed h\u1ee3p l\u00fd, c\u00f9ng v\u1edbi d\u1ecbch v\u1ee5 t\u01b0 v\u1ea5n sau ch\u1ea9n \u0111o\u00e1n b\u1edfi c\u00e1c b\u00e1c s\u0129 c\u00f3 chuy\u00ean m\u00f4n.<\/p>\n
Vi\u1ec7c l\u1ef1a ch\u1ecdn c\u00e1c c\u01a1 s\u1edf y t\u1ebf, ph\u00f2ng kh\u00e1m sinh s\u1ea3n c\u00f3 ph\u00f2ng th\u00ed nghi\u1ec7m mang l\u1ea1i nhi\u1ec1u l\u1ee3i \u00edch quan tr\u1ecdng. \u0110i\u1ec1u n\u00e0y gi\u00fap gi\u1ea3m thi\u1ec3u t\u1ed1i \u0111a nguy c\u01a1 x\u1eed l\u00fd m\u1eabu sai s\u00f3t, \u0111\u1ed3ng th\u1eddi t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 v\u00e0 \u0111\u1ed9 ch\u00ednh x\u00e1c nh\u1edd \u00e1p d\u1ee5ng c\u00e1c c\u00f4ng ngh\u1ec7 ti\u00ean ti\u1ebfn.<\/p>\n
\n $\"H\u00f4n$ <\/a>H\u00f4n nh\u00e2n c\u1eadn huy\u1ebft v\u00e0 h\u1ed9i ch\u1ee9ng Down<\/a><\/p>\n
SK\u0110S – B\u1ec7nh do th\u1eeba m\u1ed9t nhi\u1ec5m s\u1eafc th\u1ec3 s\u1ed1 21, g\u00e2y ra t\u00ecnh tr\u1ea1ng ch\u1eadm ph\u00e1t tri\u1ec3n th\u1ec3 ch\u1ea5t v\u00e0 t\u00e2m th\u1ea7n. C\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng Down c\u00f3 th\u1ec3 r\u1ea5t kh\u00e1c nhau gi\u1eefa c\u00e1c tr\u1ebb m\u1eafc b\u1ec7nh.<\/p>\n<\/div>\n
<\/p>\n
<\/p>\n","protected":false},"excerpt":{"rendered":"
N\u1ed8I DUNG 1. T\u1ea7m quan tr\u1ecdng c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down 2. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down 3. Ai n\u00ean th\u1ef1c hi\u1ec7n c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down? H\u1ed9i ch\u1ee9ng Down, hay c\u00f2n g\u1ecdi l\u00e0 Tam nhi\u1ec5m s\u1eafc […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-1084","post","type-post","status-publish","format-standard","hentry","category-gioi-tinh"],"_links":{"self":[{"href":"http:\/\/ytevn.com\/index.php?rest_route=\/wp\/v2\/posts\/1084","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/ytevn.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/ytevn.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/ytevn.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/ytevn.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1084"}],"version-history":[{"count":0,"href":"http:\/\/ytevn.com\/index.php?rest_route=\/wp\/v2\/posts\/1084\/revisions"}],"wp:attachment":[{"href":"http:\/\/ytevn.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1084"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/ytevn.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1084"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/ytevn.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1084"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}

1. T\u1ea7m quan tr\u1ecdng c\u1ee7a c\u00e1c x\u00e9t nghi\u1ec7m s\u00e0ng l\u1ecdc tr\u01b0\u1edbc sinh H\u1ed9i ch\u1ee9ng Down <\/strong><\/h2>\n\n\n \n <\/div>